Does she? We don’t see much jigging or ambling from her and no textual evidence of lisping. Maybe that’s why this line is almost always played as a general you – because it’s hard to picture Ophelia doing any of these things.
I would, though, like to see someone experiment with taking this as direction for Ophelia – finding opportunities to jig and amble, and if not to lisp, well, to try some cute-talk or baby voice. Maybe just that up-talking thing that is so popular these days could count as lisping. Though listening to Ophelia uptalk her way through the play might be impossible to bear.
Maybe if she just did it to Hamlet and talked like a normal person to everyone else.