The Hamlet Project

It’s a little late for pestilence to get that guy. He’s dead. There’s not much damage a pestilence could do at this point.
Do mad rogues typically get cursed with pestilences? Pestilenci?
And how did he die?
Is it possible that this line isn’t, in fact, a curse or an exclamation, but an explanation for his cause of death?
Did Yorick somehow fall victim to a pestilence? Is it possible he was one of the first that fell victim to the plague that caused the pocky corpses? And was it, possibly, said that he was felled by it because he was a mad rogue?