Hmm. Wealth and peace create an imposthume? An abscess? Or maybe – it’s like in the warm hospitable environment of wealth and peace, it becomes much more possible for a dark disease to grow. The way, say, a tropical island – so warm and wet can encourage a rot…but it is not the fault of the island, just the hospitality of the environment.
And in this case, Claudius is likely the disease that wealth and peace allows to multiply.
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This lines is the beginning of Hamlet’s climactic transformation, later worked out in his monologue in the same scene. If you want to play Hamlet the right way, make this line and its proceeding monologue your lifeblood.
After hearing how shamelessly the young Fortinbras is handling his Norway situation, Hamlet is jarred from his own shamelessness – his “dull revenge” (that is, his revenge plots that have failed up to this point). Hamlet remembers that his primary objective is to bring honor to his father, and he sees in Fortinbras’s shameless behavior his own shameless behavior and is disgusted with himself. His response – and the main climax of the entire play – is to stop pussyfooting around and do the job himself.
I hope your dream of being cast as Hamlet someday comes true, but if that production cuts this line, the proceeding monologue, and the whole Fortinbras subplot, run away from it and never look back.